Synthesis of Substituted Chromanones: An Organocatalytic Aldol/oxa-Michael Reaction
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چکیده
منابع مشابه
Organocatalytic enantio- and diastereoselective synthesis of highly substituted δ-lactones via a Michael-cyclization cascade.
An organocatalyzed Michael-cyclization cascade approach of readily available α,β-unsaturated aldehydes and pyrazoleamides has been developed to get highly substituted δ-lactones in excellent enantioselectivities (up to 97%) and diastereoselectivities. The δ-lactones so obtained could easily be transformed into benzazepine derivatives with excellent enantio- and diastereoselectivities. Furthermo...
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ژورنال
عنوان ژورنال: Organic Letters
سال: 2010
ISSN: 1523-7060,1523-7052
DOI: 10.1021/ol101221c